Botox is a prescription medicine that is injected into muscles and used to improve the look of the “11s,” the moderate to severe frown lines
between the eyebrows (glabellar lines). With a few tiny injections, Botox blocks nerve impulses to the injected muscles, reducing their
contractions. This reduced muscle activity helps smooth the appearance of stubborn frown lines between the brows.
What is the difference between Botox and fillers?
Frown lines are caused by overactive facial muscles. Fillers mask the wrinkle by adding volume around the muscle with intradermal injections.
Botox is intramuscular, blocking the chemicals that cause facial muscles to contract, thereby relaxing them. While there are many options
available for fillers, Botox is the only product of its type that affects the muscles that cause these wrinkles.
Be sure to discuss any medical conditions with your doctor during your initial consultation. Tell your doctor about all the medicines you
take, including prescription and nonprescription medicines, vitamins and herbal products. Avoid aspirin, ibuprofen, anti-inflammatories,
vitamin E, gingko biloba and St. John's Wort for a week before the treatment to reduce the potential for bruising or swelling. Using Botox
with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have
received Botox in the past.
During your consultation, your doctor will ask you about your goals to determine where to administer Botox. To do this, your doctor may
examine your ability to move certain muscles in your brow area. The location, size, and use of the muscles that create furrow between your
brows can vary among individuals. Ask the doctor any questions you may have about your expectations for treatment, and discuss treatment goals
and finalize a customized treatment plan tailored to your needs.
Is Botox safe?
Botox is approved by the US Food and Drug Administration (FDA), meaning that clinical data on its safety and effectiveness were reviewed by
the FDA prior to approval.
Botox is approved to treat 20 different conditions in more than 75 countries worldwide and has been approved in the US for more than 17 years
to treat a variety of medical conditions, The same formulation was approved in 2002 as Botox Cosmetic for the temporary treatment of the
stubborn vertical lines between the eyebrows, often referred to as the “11's” in people ages 18 to 65.
Are there any side effects with Botox treatment?
Following treatment with Botox, some patients have reported minimal bruising around the injection-site area. The most common side effects
following injection include headache, respiratory infection, flu syndrome, temporary eyelid droop, and nausea. Localized pain, infection,
inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection.
Patients with certain neurological disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of seriou side effects. Serious allergic reactions have been rarely reported. If you think you’re having an allergic reaction or other unusual symptoms
such as difficulty swallowing, speaking, or breathing, call your doctor immediately. Ask your physician if you have any unanswered questions,
and tell your doctor if you have any side effect that bothers you or that does not go away. You may also report side effects to FDA at
What can I expect during treatment?
Botox is quick and minimally invasive. Your doctor makes a few tiny injections into the muscles that cause moderate to severe frown lines
between your brows. Your doctor will determine exactly where to administer the injections to achieve the best results. No anesthesia is
required. However, your doctor may choose to numb the area with a cold pack or anesthetic cream prior to injecting. The entire procedure takes
approximately 10 minutes. Discomfort is usually minimal and brief - most patients compare the sensation to a bug bite. Most patients are in
and out of the physician’s office without downtime following Botox treatment. You may resume normal activity immediately.
When will I see results from the treatment?
Within 24 to 48 hours, you should start to notice a softening in the appearance of the stubborn frown lines between your brows. In clinical
trials, a majority of patients were able to see significant improvement at 7 days, continuing for up to a month. By day 30 in a patient
clinical study, 89% of patients judged the severity of their frown lines between their eyes as moderate or better. Visible results have been
shown to last up to 4 months. Individual results may vary; talk to your doctor about what you can expect.
If you're pleased with your Botox treatment, you might want to consider a regular treatment schedule to help maintain your results.
You can receive injections with Botox every 3 to 4 months to help you maintain the results as long as you don't have any serious allergic
reactions or other significant side effects. Your physician’s office may offer treatment reminders to keep you on track.
If you discontinue treatment, the moderate to severe frown lines between your brows will gradually return to look like they did before
What type of aftercare is necessary?
No downtime is needed - you're ready to get on with your day! However, you should not lie down for two hours after the treatment or rub or
massage the treated area as this may move the Botox. Also, do not exercise excessively the day of the treatment. Your physician will give you
additional specific aftercare instructions at the time of your treatment, if needed.
Will the results look natural? Will my face still have expression?
Treatments such as Botox can enhance the way you look. Botox is often used to relax the dominant frown muscles between the eyebrows,
allowing the 2 vertical lines between the brows, often referred to as the “11's”, to temporarily diminish in appearance. In fact, a National
Women's Health Resource Center survey found that for those women who were treated with or considering esthetic-injectable treatments, more
than half (52%) reported that treatments were appealing to them to obtain a “natural and refreshed” look.
When administered by an experienced physician, you can still smile, frown, and look surprised without those lines - also known as the “11's” -
between your brows. Esthetic-injectable treatments such as Botox are technique-sensitive procedures so make sure to visit a well-trained
esthetic-specialty physician for your treatment and discuss the optimal results you would like to achieve.
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